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microhuse Microbiología Clínica HUSE @microhuse ·
7 Oct

Gran calidad científica en el III Curso de Actualización en Resistencia Antibiótica, compartiendo aprendizaje y experiencias con excelentes compañeros y amigos 💪🏻🦠💊

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arpbigidisba arpbigidisba @arpbigidisba ·
3 Oct

This month, we welcomed two international students!
🇭🇷 Marina learned confocal microscopy for biofilm analysis.
🇷🇴 Alexandru joined us through Erasmus+ to study in vitro-evolved P. aeruginosa strains.

Thanks for joining us! 🧫🧬

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arpbigidisba arpbigidisba @arpbigidisba ·
3 Oct

This week at Update in Microbiology Research, our postdoc @mariangomis9 reviewed regulatory systems in P. aeruginosa and shared promising preliminary findings from her study of the CpxRS two-component system.

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arpbigidisba arpbigidisba @arpbigidisba ·
26 Sep

Ahir @idisbaib va celebrar la Nit de la Recerca 🔬✨ Una nit per apropar la ciència a tothom! N’Elena hi va participar amb un conte sobre els antibiòtics i la resistència antimicrobiana, explicant als més petits la importància de fer-ne un bon ús. 🧒🧪

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arpbigidisba arpbigidisba @arpbigidisba ·
24 Sep

🧫 Back to our Microbiological Update Sessions! Our postdoctoral researcher Maria Escobar gave a seminar on the biological cost of β-lactam resistance, exploring its impact on biofilm formation and metabolic activity in P.aeruginosa and emerging pathogens associated with CF.

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idisbaib IdISBa @idisbaib ·
17 Jul

Donam la benvinguda a Maria Escobar Salom, nova investigadora del grup @arpbigidisba de l’IdISBa.
La seva incorporació reforça la recerca en la lluita contra la resistència als antibiòtics.

Un contracte finançat per l'@AgEInves

Més informació: http://www.idisba.es

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ARPBIG - Antimicrobial Resistance and Pathogenesis of Bacterial Infections Group

Gran calidad científica en el III Curso de Actuali Gran calidad científica en el III Curso de Actualización en Resistencia Antimicrobiana, compartiendo aprendizaje y experiencias con excelentes compañeros y amigos! 💊🦠🧫

#resistenciaantibiótica #microbiologia #formacion
🌍🔬Over the past month, we have had the pleasure of 🌍🔬Over the past month, we have had the pleasure of welcoming two international students to our laboratory and sharing our research, techniques, and expertise with them.

🇭🇷 Marina, from the University of Rijeka, Department of Clinical Microbiology (Croatia), joined us to learn how to use confocal microscopy to analyse biofilms, including live/dead staining and imaging.

🇷🇴 Alexandru, from the University of Agronomic Sciences and Veterinary Medicine, joined us through the Erasmus+ programme. During his stay, he learned how we perform phenotypic and genotypic analyses of in vitro-evolved Pseudomonas aeruginosa strains.
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#InternationalStudents #ErasmusPlus #Research #Microbiology #InternationalCollaboration
This week in our Update in Microbiology Research s This week in our Update in Microbiology Research series, our postdoctoral researcher Marian Gomis gave a brief overview of regulatory systems in P. aeruginosa. 

She also shared preliminary findings from her study of the CpxRS two-component system and its potential role in resistance to novel β-lactams.
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@idisbaib @mariangomis9 #MicrobiologyResearch #PseudomonasAeruginosa #AntimicrobialResistance #CpxRS
Ahir @idisbaib va celebrar la Nit de la Recerca, u Ahir @idisbaib va celebrar la Nit de la Recerca, una nit per apropar la ciència a tothom, també als més petits. 🔬✨

N’Elena hi va participar amb un conte sobre els antibiòtics i la resistència antimicrobiana, per explicar d’una manera senzilla i divertida, per què és tan important fer-ne un bon ús.

Una manera diferent de compartir ciència i despertar la curiositat des de ben petits. 

#divulgaciócientífica #resistenciaantibióticos #microbiologia @ele_jordana
🧫 Back to our Microbiological Update Sessions afte 🧫 Back to our Microbiological Update Sessions after the summer break!

Our postdoctoral researcher Maria Escobar gave a seminar on the biological cost of β-lactam resistance, exploring its impact on biofilm formation and metabolic activity in Pseudomonas aeruginosa and emerging pathogens associated with cystic fibrosis.

The session highlighted how resistance mechanisms can shape bacterial physiology and adaptation. 🔬
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#AntimicrobialResistance #Biofilm #PseudomonasAeruginosa @meeri.1 @idisbaib
Our newly published review explores how bacteria r Our newly published review explores how bacteria respond not only to their own signals but also to hormones, neurotransmitters, other naturally occurring molecules, as well as drugs and synthetic contaminants. Some of these substances can make bacteria more virulent, highlighting why understanding these interactions is key to developing new ways to fight bacterial infections. 

#microbiology #infectiousdisease #bacterialvirulence
 @idisbaib @cjuannico @ele_jordana
Our recent collaborative study explores the potent Our recent collaborative study explores the potential of dual β-lactam therapy as a strategy to improve treatment against multidrug resistant Pseudomonas aeruginosa. 

A collaboration between @arpbig_idisba, @idisbaib, @husonespases, and Prof. Cornelia Landersdorfer’s group: Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences at Monash University, Australia.

👉🏼https://www.thelancet.com/journals/lanmic/article/PIIS2666-5247(26)00019-4/fulltext

#AntimicrobialResistance #PseudomonasAeruginosa #BetaLactams
At #EuroBiofilms26 in Guimarães, María D. Macià Ro At #EuroBiofilms26 in Guimarães, María D. Macià Romero chaired a session on emerging control strategies, highlighting the future potential of phage therapy. 
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#EuroBiofilms #Biofilms #PhageTherapy #MicrobiologyResearch @marilomacia @idisbaib
At the #EuroBiofilms26 Conference in Guimarães, El At the #EuroBiofilms26 Conference in Guimarães, Elena Jordana-Lluch presented her latest research showing that corticosteroids—commonly used to treat respiratory diseases—can influence how these biofilms develop by affecting bacterial communication, a process known as quorum sensing.

Understanding this interaction could help design new therapeutic strategies that combine current treatments with quorum sensing inhibitors to reduce biofilm formation and improve infection management.
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#EuroBiofilms #Biofilms #PseudomonasAeruginosa #QuorumSensing @idisbaib @ele_jordana
At the #EuroBiofilms26 Conference in Guimarães, Ma At the #EuroBiofilms26 Conference in Guimarães, María Fernández-Billón presented her work showing that cefiderocol is more effective against Pseudomonas aeruginosa biofilms under these low-iron conditions. However, the antibiotic was still unable to completely eradicate the biofilms because bacterial resistance mechanisms remained active, even at high concentrations.

These findings highlight both the potential and the current limitations of new antibiotics against chronic biofilm-associated infections.
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#EuroBiofilms #Biofilms #PseudomonasAeruginosa #AntimicrobialResistance @mfbillon
This week, our Master’s student from the Universit This week, our Master’s student from the University of Antwerp, Amélie Bell, successfully defended her Master’s thesis entitled “Emerging Mechanisms of Resistance to β-Lactam Antibiotics in Pseudomonas aeruginosa”.

The work investigates the different routes through which this pathogen develops resistance to nearly all β-lactam antibiotics, one of the most widely used classes of antimicrobial agents.

Congratulations on an excellent defense and on the outstanding work accomplished.
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#AntimicrobialResistance #PseudomonasAeruginosa #BetaLactamResistance @idisbaib @uantwerpen
🎓🔬 Enhorabuena a la Dra. María Montaner por la def 🎓🔬 Enhorabuena a la Dra. María Montaner por la defensa de su tesis doctoral, centrada en el estudio de cómo los antibióticos β-lactámicos actúan frente a Pseudomonas aeruginosa, una bacteria clave en el contexto de la resistencia antimicrobiana.

Sus hallazgos contribuyen a una mejor comprensión de los mecanismos de acción de estos antibióticos y abren nuevas vías para optimizar su uso en el tratamiento de infecciones complejas y difíciles de tratar.
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#TesisDoctoral #ResistenciaAntimicrobiana #PseudomonasAeruginosa #SomSalut @idisbaib @uibuniversitat
At the Update in Microbiology Research Sessions, D At the Update in Microbiology Research Sessions, Dr. Pablo Fraile @pablofribot presented the preliminary results of the IBPAP Study, offering new insights into tick-borne diseases in the Balearic Islands.

The study includes the macroscopic and microbiological characterization of ticks, together with the clinical assessment and follow-up of patients after tick bites. An interesting and valuable contribution to ongoing research in vector-borne diseases. 
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#TickBorneDiseases #VectorBorneDiseases #MicrobiologyResearch @idisba @sonespases @pablofribot
In this work, we characterized how the V516M mutat In this work, we characterized how the V516M mutation in PBP2 drastically increases resistance to zidebactam and drives cross-resistance with nacubactam, while compounds like durlobactam and imipenem remain largely unaffected. Interestingly, although this mutation triggers distinct changes in cell morphology, it does not compromise the bacteria’s growth rate or virulence. Crucially, zidebactam retains its function as an AmpC inhibitor, meaning its combination with cefepime remains an excellent therapeutic option to restore susceptibility. 

A vital step forward in understanding target modifications and guiding the design of future antimicrobials! 👏

👉🏼 https://doi.org/10.1128/aac.00346-26
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#PseudomonasAeruginosa #AntimicrobialResistance #Microbiology #AntibioticResearch @msastre88 @mariangomis9 @almudena.fm @_dani_s99 @thormeu79 @antoniooliver1973 @idisbaib
Our predoctoral researcher, Paula Ordoñez, attende Our predoctoral researcher, Paula Ordoñez, attended ASM Microbe 2026 in Washington, D.C. as the ASM Young Ambassador to Spain.

As part of the Young Ambassadors Program, she participated in networking sessions and discussions with ambassadors from around the world, exchanging experiences and ideas on scientific leadership, international collaboration, outreach activities, mentoring, and strategies to strengthen the impact of microbiology within local and global communities.

Paula also presented a poster on her research, sharing her work with the international microbiology community and fostering valuable scientific discussions and collaborations.
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#ASMMicrobe2026 #ASMYoungAmbassador #InternationalCollaboration 
@idisbaib @asmicrobiology @paulaordjim @experimental_therapeutics @thormeu79
Today, in the Clinical Microbiology updates sessio Today, in the Clinical Microbiology updates session, Almudena presented the “PSEUDOBACT” project: a prospective study of Pseudomonas aeruginosa bloodstream infections (BSI) in a multidrug-resistant (MDR) setting. By integrating clinical outcomes with clonality, resistance mechanisms, and virulence traits, the study aims to identify optimal β-lactam treatment strategies to improve BSI outcomes.
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#Microbiology #AMR #PAeruginosa #BSI
@idisbaib @husonespases @almudena.fm
This week, at the Update in Microbiology Research This week, at the Update in Microbiology Research Sessions, Maria Fernández-Billón presented her work on strategies to combat Pseudomonas aeruginosa biofilms and potential therapies to inhibit their growth, with a particular focus on treatment using cefiderocol. A very interesting session! 🔬🦠 @idisbaib @husonespases 

#microbiologia #antimicrobialresistance #biofilm #pseudomonasaeruginosa
Jordi además presentó el trabajo de la Dra. Elena Jordi además presentó el trabajo de la Dra. Elena Jordana @ele_jordana sobre el aislamiento de fagos activos frente a clones epidémicos de Pseudomonas aeruginosa, a partir de una colección de cepas genéticamente caracterizadas de este patógeno. @idisbaib

#seimc #microbiologia #medicina #investigación #cienciasalud
Joan Bosch presentó un trabajo sobre el efecto de Joan Bosch presentó un trabajo sobre el efecto de “Kaftrio” en la microbiología de la fibrosis quística, analizando cómo este tratamiento puede modificar la colonización bacteriana en los pulmones, explorando así los cambios en el equilibrio microbiano tras la terapia. @husonespases

#seimc #microbiologia #medicina #investigación #cienciasalud
Biel Taltavull presentó un estudio centrado en el Biel Taltavull presentó un estudio centrado en el desarrollo de una herramienta de PCR en tiempo real para la detección rápida de clones de alto riesgo de Pseudomonas aeruginosa directamente de muestras clínicas. Este tipo de avances permite mejorar la vigilancia epidemiológica en el entorno hospitalario y podría facilitar una detección más precoz de infecciones, contribuyendo a una mejor toma de decisiones clínicas y a la prevención de brotes. @idisbaib @consorcio_ciber @husonespases

#seimc #microbiologia #medicina #investigación #cienciasalud
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