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arpbigidisba arpbigidisba @arpbigidisba ·
19h

This week at the Update in Clinical Microbiology seminar, Daniela presented her research on plasmid-mediated resistance in Neisseria gonorrhoeae, with a strong focus on ESBLs such as TEM-93, a novel putative resistance mechanism. #AMR #clinicalresearch #NeisseriaGonorrhoeae

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arpbigidisba arpbigidisba @arpbigidisba ·
27 Apr

She also contributed to #ESCMIDGlobal with a presentation in a study group business meeting.
As Secretary of the ESGB EC, she participated in the group's meeting, summarising the Bratislava on-site meeting and enhancing liaisons and collaborations on biofilm-related infections.

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arpbigidisba arpbigidisba @arpbigidisba ·
27 Apr

Dr. María Dolores Macià
also contributed to #ESCMIDGlobal with a scientific poster, presenting preliminary results from a cervical cancer screening study using vaginal self-sampling and molecular detection of high-risk HPV genotypes.
#ESCMID #HPV #ESGB #Biofilm

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arpbigidisba arpbigidisba @arpbigidisba ·
27 Apr

Dr. Antonio Oliver @aoliverp73
Science Officer of ESGARS, participated in the ESGARS session at #ESCMIDGlobal. The meeting highlighted the group's role in AMR resistance surveillance and its importance for global monitoring and collaboration.
#AMR #ESCMID #ESGARS

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arpbigidisba arpbigidisba @arpbigidisba ·
27 Apr

Results from an international
collaborative research project with Monash University were presented at #ESCMIDGlobal as a poster by Cornelia Landersdorfer. The study shows how different resistance mechanisms shape the response of Pseudomonas aeruginosa HRC to ATB treatments.

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arpbigidisba arpbigidisba @arpbigidisba ·
27 Apr

Miquel Angel Sastre Femenia
@Msastre88 presented his research on an oral session at #ESCMIDGlobal, shedding light on mechanisms of zidebactam resistance in Pseudomonas aeruginosa.
#AMR #ESCMID #PseudomonasAeruginosa #PBP2

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ARPBIG - Antimicrobial Resistance and Pathogenesis of Bacterial Infections Group

This week, at the Update in Clinical Microbiology This week, at the Update in Clinical Microbiology seminar, Daniela presented her research on plasmid-mediated resistance in Neisseria gonorrhoeae, with a strong focus on ESBLs such as TEM-93, a novel putative resistance mechanism. #amr #clinicalresearch #neisseriagonorrhoeae @idisbaib
🧫 Xavier Mulet @xavi1239 presented his work at #ES 🧫 Xavier Mulet @xavi1239 presented his work at #ESCMIDGlobal on an innovative AI-based approach for the rapid detection of high-risk Pseudomonas aeruginosa clones using MALDI-TOF spectra.

Using a large collection of clinical isolates, the study developed a predictive model capable of accurately identifying major MDR/XDR high-risk clones such as ST175, ST235, ST111 and the emerging ST773.

This approach provides a fast and powerful tool to support infection control and improve clinical decision-making, enabling more targeted and timely therapeutic strategies.

#AMR #ESCMID #PseudomonasAeruginosa
🧫 Daniela Salazar @_dani_s99 presented a poster at 🧫 Daniela Salazar @_dani_s99 presented a poster at #ESCMIDGlobal, with key contributions from Alba Quesada @albaa.qm, on the evolutionary potential of β-lactam resistance in Neisseria gonorrhoeae.

The study shows that, under β-lactam pressure, resistant subpopulations can emerge with increased MICs and cross-resistance to multiple antibiotics, including cephalosporins and carbapenems. Notably, these changes were not driven by mutations in TEM-1 or TEM-135 β-lactamases, but likely by chromosomal adaptations and other regulatory mechanisms.

These findings highlight the complexity of resistance evolution and reinforce the need for genomic surveillance and alternative therapeutic strategies against N. gonorrhoeae.

#AMR #ESCMID #NeisseriaGonorrhoeae
@experimental_therapeutics @thormeu79 @albaa.qm
🧫 Enrique Ruiz de Gopegui presented this work at # 🧫 Enrique Ruiz de Gopegui presented this work at #ESCMIDGlobal, evaluating the diagnostic capacity of clinical microbiology laboratories to detect carbapenemase-producing bacteria within the SEIMC Quality Control Program.

Analysing data from 2008 to 2025, the results show a clear improvement in carbapenemase detection over time, with participating centres increasingly able to correctly identify these resistance mechanisms.

This progress likely reflects advances in diagnostic tools—such as automated systems, immunochromatography and PCR—as well as continuous training efforts supported by the SEIMC Quality Control Program.

#AMR #ESCMID #Carbapenemases #SEIMC
🧫 Paula Ordoñez @paulaordjim presented her work at 🧫 Paula Ordoñez @paulaordjim presented her work at #ESCMIDGlobal on the evolutionary dynamics of antimicrobial resistance in Neisseria gonorrhoeae under ceftriaxone and azithromycin pressure.

Her study shows that resistance evolution is shaped by both the initial bacterial genotype and the treatment regimen. While dual therapy constrains the maximum resistance levels to β-lactams, it can also select for hypermutator strains, influencing adaptation pathways.

These findings highlight the importance of genotype-guided therapeutic strategies to better preserve antibiotic efficacy against N. gonorrhoeae.

#AMR #ESCMID #NeisseriaGonorrhoeae
@experimental_therapeutics @thormeu79
🧫 Miquel Àngel Sastre-Femenia @msastre88 presented 🧫 Miquel Àngel Sastre-Femenia @msastre88 presented his latest research during an oral session at #ESCMIDGlobal, shedding light on mechanisms of zidebactam resistance in Pseudomonas aeruginosa.

His work identifies the V516M mutation in PBP2 as a key driver of zidebactam resistance, significantly reducing binding affinity and altering susceptibility profiles. Importantly, cross-resistance patterns were shown to depend on PBP-binding interactions, impacting some antibiotics while leaving others unaffected.

These findings highlight the complexity of antimicrobial resistance and emphasize the importance of detailed PBP-binding profiling to guide future therapeutic strategies.

#AMR #ESCMID #PseudomonasAeruginosa #PBP2
🧫 Results from an international collaborative rese 🧫 Results from an international collaborative research project with Monash University were presented at #ESCMIDGlobal as a poster by Cornelia Landersdorfer.

The study explored how different resistance mechanisms shape the response of high-risk Pseudomonas aeruginosa clones to antibiotic treatments, highlighting the need for more tailored therapeutic strategies.

#AMR #ESCMID #PseudomonasAeruginosa
🧫 Antonio Oliver @antoniooliver1973 Science Office 🧫 Antonio Oliver @antoniooliver1973 Science Officer of ESGARS, participated in the ESGARS session at #ESCMIDGlobal.

The meeting highlighted the group’s role in antimicrobial resistance surveillance and its importance for global monitoring and collaboration.

🔗 ESGARS LinkedIn: https://www.linkedin.com/company/esgars-escmid-study-group-for-antibiotic-resistance

#AMR #ESCMID #ESGARS
🧫 María Dolores Macià @marilomacia also contribute 🧫 María Dolores Macià @marilomacia also contributed to #ESCMIDGlobal with a scientific poster.

As microbiologist in charge of the Molecular Microbiology section, she presented preliminary results from a cervical cancer screening study using vaginal self-sampling and molecular detection of high-risk HPV genotypes.

The analysis highlights the prevalence of non-16/18 HPV genotypes, supporting the value of genotyping and comprehensive molecular screening strategies to enhance prevention efforts.

#ESCMID #HPV #ESGB #Biofilm
🧫 María Dolores Macià @marilomacia contributed to 🧫 María Dolores Macià @marilomacia contributed to #ESCMIDGlobal through a presentation in a study group business meeting.

As Secretary of the ESGB EC, she participated in the group’s business meeting, summarising highlights of the Bratislava on-site meeting (April newsletter) and enhancing liaisons and collaborations on biofilm-related infections research.

🔗 LinkedIn ESGB: https://www.linkedin.com/groups/18599002/ 

#ESCMID #ESGB #Biofilm
Today our colleague Fabiola Expósito presented on Today our colleague Fabiola Expósito presented on emerging therapeutic strategies against antimicrobial-resistant gonorrhea. She shared the latest advances in treatments for MDR Neisseria gonorrhoeae, highlighting recent alternatives to consider for the future. 

A crucial and timely topic addressing one of the most pressing global health challenges. @idisbaib #research #globalhealth #antimicrobialresistance #gonorrhea
Breaking down the essentials of Viral Hemorrhagic Breaking down the essentials of Viral Hemorrhagic Fevers 🦠

Eugenia Cabrera @eug.niia shared an overview, diving into the latest protocols and current approaches to management and response.
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#HospitalUniversitariSonEspases #SomSalut #InfectiousDiseases
En la Jornada del Cáncer de Cérvix, mediante la po En la Jornada del Cáncer de Cérvix, mediante la ponencia de la Dra. Mariló Maciá @marilomacia, en la que se presentaron resultados preliminares del cribado de VPH en Baleares, se destacó el papel esencial del diagnóstico microbiológico y del genotipado en la detección precoz y en la toma de decisiones clínicas.
@idisbaib @husonespases @husonllatzer @salutpublicaib
Last Wednesday, Juan Bosch, explained how molecula Last Wednesday, Juan Bosch, explained how molecular techniques such as LAMP are revolutionizing pneumonia diagnosis, complementing traditional bacterial culture methods to achieve faster and more accurate results. Great presentation, congratulations!
Nuestros estudiantes de doctorado Paula, Jordi, Bi Nuestros estudiantes de doctorado Paula, Jordi, Biel y Paola han presentado algunos resultados de sus tesis doctorales en las III Jornadas del Programa de Doctorado en Microbiología Ambiental y Biomédica. 

¡Enhorabuena por el gran trabajo! 👏🔬 
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@idisba @uibuniversitat @isciiisalud #postgrauuib #IBFonsEu #ibFSEPLUSeu #illesbalearssostenibles
La Dra. Isabel Maria Barceló presentó los resultad La Dra. Isabel Maria Barceló presentó los resultados de su último artículo publicado, en el que se analiza cómo las benzodiazepinas (fármacos comunes en sedación) alteran la fisiología de Pseudomonas aeruginosa, sobre todo en cuanto a la formación de biofilm. ¡Enhorabuena por este gran trabajo! @idisbaib @uibuniversitat @bel.barcelo
Happy to announce the publication in #AACJournal ( Happy to announce the publication in #AACJournal (journals.asm.org/doi/10.1128/aa…) of The Pseudomonas aeruginosa Resistome Explorer (PaREx), an open-source, Python-based pipeline designed for the automated analysis of P. aeruginosa resistomes. Availabe at github.com/ARPBIGIDISBA/PaREx

It also includes the web tool PDC (Pseudomonas Derived Cephalosporinase) analyzer designed to characterize P. aeruginosa AmpC sequences and determine the role in resistance to novel beta-lactams  pdc.arpbigidisba.com

Thanks to the organizations that made this possible: @idisbaib @husonespases @consorcio_ciber #JPIAMR #MePRAM #ciberinfec
Esta mañana, la Dra. @marilomacia ha impartido un Esta mañana, la Dra. @marilomacia ha impartido un seminario en el @idisbaib @husonespases , donde ha compartido su visión de la investigación traslacional y la microbiología asistencial durante su período de Intensificación de la Actividad Investigadora Ramón Llull.
This week, in our research update sessions, Eva Al This week, in our research update sessions, Eva Alcoceba presented the SCOUT study: Clinical effectiveness and bacteriological eradication of four short-course antibiotic regimens for lower UTIs in adult women.

Thank you, Eva! 👏🔬
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@idisbaib @husonespases
This week, Biel Taltavull presented an ongoing pro This week, Biel Taltavull presented an ongoing project on the development and validation of a real-time PCR assay to identify high-risk P. aeruginosa clones directly from clinical samples. Excellent and highly impactful research! @consorcio_ciber @isciiisalud @idisbaib
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