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In vitro dynamics and mechanisms of cefiderocol resistance development in wild-type, mutator and XDR Pseudomonas aeruginosa
(0)María A Gomis-Font1 , Miquel À Sastre-Femenia1 , Biel Taltavull1 , Gabriel Cabot1 , Antonio Oliver1 1 Servicio de Microbiología y Unidad de Investigación, Hospital Universitari Son Espases, Instituto de Investigación Sanitaria Illes Balears (IdISBa), CIBERINFEC, Palma de Mallorca, Spain. Objectives: To analyse the dynamics and mechanisms of stepwise resistance development to cefiderocol in Pseudomonas… Read More ›
In vitro activity of human defensins HNP-1 and hBD-3 against multidrug-resistant ESKAPE Gram-negatives of clinical origin and selected peptidoglycan recycling-defective mutants
María Escobar-Salom#, 1, 2, 3 , Isabel María Barceló#, 1, 2, 3, Estrella Rojo-Molinero1, 2, 3, Elena Jordana-Lluch1, 2, 3, Gabriel Cabot1, 2, 3 , Antonio Oliver1, 2, 3, Carlos Juan1, 2, 3 1 Research Unit, University Hospital Son Espases-Health Research Institute of the Balearic Islands (IdISBa), Palma, Spain. 2 Microbiology Department, University Hospital Son… Read More ›
Penicillin-Binding Protein Occupancy Dataset for 18 β-Lactams and 4 β-Lactamase Inhibitors in Neisseria gonorrhoeae
Silvia López-Argüello 1, Maria Montaner 1, Amanda Mármol-Salvador 1, Ana Velázquez-Escudero 2, 3, Fernando Docobo-Pérez 2, 3, 4, Antonio Oliver 1, 4, Bartolome Moya 1, 4 1 Servicio de Microbiología and Unidad de Investigación, Hospital Universitario Son Espases, Health Research Institute of the Balearic Islands (IdISBa), Palma, Spain. 2 Departamento de Microbiología, Facultad de Medicina,… Read More ›
Biochemical Insights into Imipenem Collateral Susceptibility Driven by ampC Mutations Conferring Ceftolozane/Tazobactam Resistance in Pseudomonas aeruginosa
Gabriel Cabot 1, Kihun Kim 2, Brian L. Mark 2, Antonio Oliver1, Mazdak Khajehpour 3 1Research Unit, University Hospital Son Espases – Health Research Institute of the Balearic Islands (IdISBa), Palma, Spain. 2Department of Microbiology, University of Manitoba, Winnipeg, Canada. 3Department of Chemistry, University of Manitoba, Winnipeg, Canada. Abstract: Several Pseudomonas aeruginosa AmpC mutants have… Read More ›
Antibiotic Resistance and Pathogenicity of Bacterial Infections Group 