González J; de Batlle J; Benítez ID; Torres G; Santisteve S; Targa ADS; Gort-Paniello C; Moncusí-Moix A; Aguilà M; Seck F; Ceccato A; Ferrer R; Motos A; Riera J; Fernández L; Menéndez R; Lorente JÁ; Peñuelas O; Garcia-Gasulla D; Peñasco Y; Ricart P; Abril Palomares E; Aguilera L; Rodríguez A; Boado Varela MV; Beteré B; Pozo-Laderas JC; Solé-Violan J; Salvador-Adell I; Novo MA; Barberán J; Amaya Villar R; Garnacho-Montero J; Gómez JM; Blandino Ortiz A; Tamayo Lomas L; Úbeda A; Catalán-González M; Sánchez-Miralles A; Martínez Varela I; Jorge García RN; Franco N; Gumucio-Sanguino VD; Bustamante-Munguira E; Valdivia LJ; Caballero J; Gallego E; Rodríguez C; Castellanos-Ortega Á; Trenado J; Marin-Corral J; Albaiceta GM; de la Torre MDC; Loza-Vázquez A; Vidal P; Añón JM; Carbajales Pérez C; Sagredo V; Carbonell N; Socias L; Barberà C; Estella A; Diaz E; de Gonzalo-Calvo D; Torres A; Barbé F

Abstract: Critical COVID-19 survivors have a high risk of respiratory sequelae. Therefore, we aimed to identify key factors associated with altered lung function and CT scan abnormalities at a follow-up visit in a cohort of critical COVID-19 survivors. Multicenter ambispective observational study in 52 Spanish intensive care units. Up to 1327 PCR-confirmed critical COVID-19 patients had sociodemographic, anthropometric, comorbidity and lifestyle characteristics collected at hospital admission; clinical and biological parameters throughout hospital stay; and, lung function and CT scan at a follow-up visit. The median [p25-p75] time from discharge to follow-up was 3.57 [2.77-4.92] months. Median age was 60 [53-67] years, 27.8% women. The mean (SD) percentage of predicted diffusing lung capacity for carbon monoxide (DLCO) at follow-up was 72.02 (18.33)% predicted, with 66% of patients having DLCO<80% and="and" 24%="24%" having="having" DLCO="DLCO">2023 doi: 10.1016/j.arbres.2022.12.017 https://pubmed.ncbi.nlm.nih.gov/36690515