Institut d'Investigació Sanitària Illes Balears (IdISBa) Research Group.

Publications rss

Penicillin-Binding Protein Occupancy Dataset for 18 β-Lactams and 4 β-Lactamase Inhibitors in Neisseria gonorrhoeae

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April 26, 2023

Silvia López-Argüello 1, Maria Montaner 1, Amanda Mármol-Salvador 1, Ana Velázquez-Escudero 2, 3, Fernando Docobo-Pérez 2, 3, 4, Antonio Oliver 1, 4, Bartolome Moya 1, 4 1 Servicio de Microbiología and Unidad de Investigación, Hospital Universitario Son Espases, Health Research Institute of the Balearic Islands (IdISBa), Palma, Spain. 2 Departamento de Microbiología, Facultad de Medicina,… Read More ›

In vitro evolution of cefepime/zidebactam (WCK 5222) resistance in Pseudomonas aeruginosa: dynamics, mechanisms, fitness trade-off and impact on in vivo efficacy

Isabel Barceló 1, Gabriel Cabot 1, Snehal Palwe 2, Prashant Joshi 2, Swapna Takalkar 2, Hariharan Periasamy 2, Sara Cortés-Lara 1, Laura Zamorano 1, Irina Sánchez-Diener 1, Bartolome Moya 1, Sachin Bhagwat 2, Mahesh Patel 2, Antonio Oliver 1 1 Servicio de Microbiología y Unidad de Investigación, Hospital Universitari Son Espases, Instituto de Investigación Sanitaria… Read More ›

Comparative analysis of in vitro dynamics and mechanisms of ceftolozane/tazobactam and imipenem/relebactam resistance development in Pseudomonas aeruginosa XDR high-risk clones

María A Gomis-Font 1, 2, Gabriel Cabot 1, 2, Silvia López-Argüello 1, Laura Zamorano 1, 2, Carlos Juan 1, 2, Bartolomé Moyá 1, 2, Antonio Oliver 1, 2 1 Servicio de Microbiología y Unidad de Investigación, Hospital Universitari Son Espases, Instituto de Investigación Sanitaria Illes Balears (IdISBa), Palma de Mallorca, Spain. 2 CIBER en Enfermedades… Read More ›

A Genomic Snapshot of the SARS-CoV-2 Pandemic in the Balearic Islands

Carla López-Causapé 1, 2, Pablo A Fraile-Ribot 1, 2, Santiago Jiménez-Serrano 1 , Gabriel Cabot 1, 2, Ester Del Barrio-Tofiño 1, 2, M Carmen Prado 1, Juana María Linares 1, Aranzazu López 4, Adoración Hurtado 4, Elena Riera 5, Antoni Serra 5, Eva Roselló 6, Lluis Carbó 6, M Victoria Fernández-Baca 7, Carmen Gallegos 7,… Read More ›

Whole-genome sequence-guided PCR for the rapid identification of the Pseudomonas aeruginosa ST175 high-risk clone directly from clinical samples

Gabriel Cabot 1, Paula Lara-Esbrí 1, Xavier Mulet 1, Antonio Oliver 1 1 Servicio de Microbiología and Unidad de Investigación, Hospital Universitari Son Espases, Instituto de Investigación Sanitaria Illes Balears (IdISBa), Palma de Mallorca, Spain. Abstract: Objectives: Pseudomonas aeruginosa frequently show MDR/XDR profiles, which are associated with worldwide-disseminated high-risk clones (HRCs). We developed a PCR… Read More ›

Activity of Imipenem-Relebactam against a Large Collection of Pseudomonas aeruginosa Clinical Isolates and Isogenic β-Lactam-Resistant Mutants

Pablo A Fraile-Ribot 1, Laura Zamorano 1, Rocío Orellana 1, Ester Del Barrio-Tofiño 1, Irina Sánchez-Diener 1, Sara Cortes-Lara 1, Carla López-Causapé 1, Gabriel Cabot 1, Germán Bou 3, Luis Martínez-Martínez 4, Antonio Oliver 2; GEMARA-SEIMC/REIPI Pseudomonas Study Group 1Servicio de Microbiología, Hospital Son Espases, Instituto de Investigación Sanitaria Illes Balears (IdISBa), Palma de Mallorca,… Read More ›

Effective inhibition of PBPs by cefepime and zidebactam in the presence of VIM-1 drives potent bactericidal activity against MBL-expressing Pseudomonas aeruginosa

Bartolome Moya 1, Sachin Bhagwat 2, Gabriel Cabot 1, German Bou 3, Mahesh Patel 2, Antonio Oliver 1 1 Servicio de Microbiologia and Unidad de Investigacion, Hospital Universitario Son Espases, Instituto de Investigacion Sanitaria Illes Balears (IdISBa), Palma de Mallorca, Spain. 2 Wockhardt Research Centre, Aurangabad, India. Servicio de Microbiologia, Complejo Hospitalario Universitario A Coruña,… Read More ›

Comparative Analysis of Peptidoglycans From Pseudomonas aeruginosa Isolates Recovered From Chronic and Acute Infections

Gabriel Torrens 1, María Escobar-Salom 1, Elisabet Pol-Pol 1, Cristina Camps-Munar 1, Gabriel Cabot 1, Carla López-Causapé 1, Estrella Rojo-Molinero 1, Antonio Oliver 1, Carlos Juan 1 1Servicio de Microbiología and Unidad de Investigación, Hospital Universitari Son Espases-Institut de Investigació Sanitària de Balears (IdISBa), Palma, Spain. Abstract: Pseudomonas aeruginosa is one of the first causes… Read More ›

Profiling the susceptibility of Pseudomonas aeruginosa strains from acute and chronic infections to cell-wall-targeting immune proteins

Gabriel Torrens 1, Isabel M Barceló 1, Marcelo Pérez-Gallego 1, Maria Escobar-Salom 1, Sara Tur-Gracia 1, Marta Munar-Bestard 1, María Del Mar González-Nicolau 1, Yoandy José Cabrera-Venegas 1, Estefany Nayarith Rigo-Rumbos 1, Gabriel Cabot 1, Carla López-Causapé 1, Estrella Rojo-Molinero 1, Antonio Oliver 1, Carlos Juan 2 1Servicio de Microbiología and Unidad de Investigación, Hospital… Read More ›

In Vitro and In Vivo Activities of β-Lactams in Combination with the Novel β-Lactam Enhancers Zidebactam and WCK 5153 against Multidrug-Resistant Metallo-β-Lactamase-Producing Klebsiella pneumoniae

Bartolome Moya 1, Isabel M Barcelo 2, Gabriel Cabot 2, Gabriel Torrens 2, Snehal Palwe 2, Prashant Joshi 3, Kushal Umarkar 3, Swapna Takalkar 3, Hariharan Periasamy 3, Sachin Bhagwat 3, Mahesh Patel 3, German Bou 4, Antonio Oliver 2 1Center for Pharmacometrics and Systems Pharmacology, Department of Pharmaceutics, College of Pharmacy, University of Florida,… Read More ›

ARPBIG IdISBa

Dr. Bartolome Moyà

Instituto de Investigación Sanitaria Illes Balears