Penicillin-Binding Protein Occupancy Dataset for 18 β-Lactams and 4 β-Lactamase Inhibitors in Neisseria gonorrhoeae
López-Argüello Silvia; Montaner Maria; Mármol-Salvador Amanda; Velázquez-Escudero Ana; Docobo-Pérez Fernando; Oliver Antonio; Moya Bartolome
Abstract: The manuscript represents the first N. gonorrhoeae PBP-binding data set for 22 chemically different drugs in two type strains with different genetic background. We have identified three clusters of drugs according to their PBP binding IC 50 s and highlighted the binding differences across the two strains studied. Microbiology Spectrum: 2023 doi: 10.1128/spectrum.00692-23 https://doi.org/doi: 10.1128/spectrum.00692-23