Mensa J; Barberán J; Ferrer R; Borges M; Rascado P; Maseda E; Oliver A; Marco F; Adalia R; Aguilar G; Estella A; León López R; Robles Marcos MS; González de Molina FJ; Serrano García R; Salavert M; Fernández Gómez J; Poliakova Y; Pasquau J; Azanza JR; Bou Arévalo G; LLinares Mondéjar P; Cardinal-Fernández P; Soriano A

Abstract: Severe infection and its evolution to sepsis are becoming more prevalent every day and are among the leading causes of critical illness and mortality. Proper management is crucial to improve prognosis. This document addresses three essential points that have a significant impact on this objective: a) early recognition of patients with sepsis criteria, b) identification of those patients who suffer from an infection and have a high risk of progressing to sepsis, and c) adequate selection and optimization of the initial antimicrobial treatment. Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia: 2021 doi: 10.37201/req/126.2021 https://pubmed.ncbi.nlm.nih.gov/34693705