Optimization of a meropenem plus tobramycin combination dosage regimen against hypermutable and non-hypermutable Pseudomonas aeruginosa via mechanism-based modeling and the hollow-fiber infection model.
Landersdorfer CB1,2, Rees VE3,2, Yadav R3, Rogers KE3,2, Kim TH4, Bergen PJ2, Cheah SE3, Boyce JD5, Peleg AY5,6, Oliver A7,…