Research production

María Escobar-Salom#, 1, 2, 3 , Isabel María Barceló#, 1, 2, 3, Estrella Rojo-Molinero1, 2, 3, Elena Jordana-Lluch1, 2, 3, Gabriel Cabot1, 2, 3 , Antonio Oliver1, 2, 3, Carlos...

In vitro dynamics and mechanisms of cefiderocol resistance development in wild-type, mutator and XDR Pseudomonas aeruginosa

María A Gomis-Font1 , Miquel À Sastre-Femenia1 , Biel Taltavull1 , Gabriel Cabot1 , Antonio Oliver1 1 Servicio de Microbiología y Unidad de Investigación, Hospital Universitari Son Espases, Instituto de...

Eurobiofilms 2022: A translational perspective of biofilm-related persistent infections.

Macià MD; Borghi E; Oliver A Abstract: Biofilm: 2024 doi: 10.1016/j.bioflm.2023.100168 https://pubmed.ncbi.nlm.nih.gov/39011151...

Gut microbiome and plasma lipidome analysis reveals a specific impact of Clostridioides difficile infection on intestinal bacterial communities and sterol metabolism.

Arcay R; Barceló-Nicolau M; Suárez L; Martín L; Reigada R; Höring M; Liebisch G; Garrido C; Cabot G; Vílchez H; Cortés-Lara S; González de Herrero E; López-Causapé C; Oliver A;...

The effects of single and multiple resistance mechanisms on bacterial response to meropenem.

Fuhs DT; Cortés-Lara S; Tait JR; Rogers KE; López-Causapé C; Lee WL; Shackleford DM; Nation RL; Oliver A; Landersdorfer CB Abstract: Meropenem is commonly used against Pseudomonas aeruginosa. Traditionally, the...

Impact of chromosomally encoded resistance mechanisms and transferable β-lactamases on the activity of cefiderocol and innovative β-lactam/β-lactamase inhibitor combinations against Pseudomonas aeruginosa.

González-Pinto L; Alonso-García I; Blanco-Martín T; Camacho-Zamora P; Fraile-Ribot PA; Outeda-García M; Lasarte-Monterrubio C; Guijarro-Sánchez P; Maceiras R; Moya B; Juan C; Vázquez-Ucha JC; Beceiro A; Oliver A; Bou G;...

Impact of multidrug resistance on the virulence and fitness of Pseudomonas aeruginosa: a microbiological and clinical perspective.

Sendra E; Fernández-Muñoz A; Zamorano L; Oliver A; Horcajada JP; Juan C; Gómez-Zorrilla S Abstract: Pseudomonas aeruginosa is one of the most common nosocomial pathogens and part of the top...

Differential contribution of PBP occupancy and efflux on the effectiveness of β-lactams at their target site in clinical isolates of Neisseria gonorrhoeae.

López-Argüello S; Alcoceba E; Ordóñez P; Taltavull B; Cabot G; Gomis-Font MA; Oliver A; Moya B Abstract: Neisseria gonorrhoeae exhibits alarming antibiotic resistance trends and poses a significant challenge in...

Genomic virulence markers are associated with severe outcomes in patients with Pseudomonas aeruginosa bloodstream infection.

Valik JK; Giske CG; Hasan B; Gozalo-Margüello M; Martínez-Martínez L; Premru MM; Martinčič Ž; Beović B; Maraki S; Zacharioudaki M; Kofteridis D; McCarthy K; Paterson D; Cueto M; Morales I;...

2023

Whole-genome sequence-guided PCR for the rapid identification of the Pseudomonas aeruginosa ST175 high-risk clone directly from clinical samples

Gabriel Cabot 1, Paula Lara-Esbrí 1, Xavier Mulet 1, Antonio Oliver 1 1 Servicio de...

Whole Genome Sequencing Evidences High Rates of Relapse in Clostridioides difficile Infection Caused by the Epidemic Ribotype 106

Suárez-Bode Loreto; López-Causapé Carla; Arcay Ricardo M.; Oliver Antonio; Mena Ana Abstract: An increasing prevalence...

Visible-Light-Activated Molecular Machines Kill Fungi by Necrosis Following Mitochondrial Dysfunction and Calcium Overload.

Santos AL; Beckham JL; Liu D; Li G; van Venrooy A; Oliver A; Tegos GP;...

Vaccines against monkeypox.

Reina J; Iglesias C Abstract: The monkeypox virus is a virus that has 90% genomic...

Transmitted drug resistance to antiretroviral drugs in Spain during the period 2019-2021.

Viñuela L; de Salazar A; Fuentes A; Serrano-Conde E; Falces-Romero I; Pinto A; Portilla I;...

To update or not to update the ESCMID guidelines for the diagnosis and treatment of biofilm infections – That is the question! The opinion of the ESGB board.

Høiby N; Moser C; Oliver A; Williams C; Ramage G; Borghi E; Azeredo J; Macia...

The new generation of messenger RNA (mRNA) vaccines against influenza.

Reina J Abstract: Today there are multiple types of flu vaccines. The emergence of nucleic...

The molecular epidemiology of SARS-CoV-2 in the Pityusic Islands shows multiple introductions and fast replacements of variants in a touristic worldwide hot spot.

Viver T; López-Causapé C; Ribot-Fraile P; Pérez-Mazón C; López-Solé D; Jiménez-Guerra G; Taltavull B; López-López...

The CARBA-MAP study: national mapping of carbapenemases in Spain (2014-2018).

Gracia-Ahufinger I; López-González L; Vasallo FJ; Galar A; Siller M; Pitart C; Bloise I; Torrecillas...

The balance between antibiotic resistance and fitness/virulence in Pseudomonas aeruginosa: an update on basic knowledge and fundamental research.

Jordana-Lluch E; Barceló IM; Escobar-Salom M; Estévez MA; Zamorano L; Gómez-Zorrilla S; Sendra E; Oliver...

Spanish Antibiogram Committee (COESANT) recommendations for cumulative antibiogram reports.

Larrosa MN; Canut-Blasco A; Benito N; Cantón R; Cercenado E; Docobo-Pérez F; Fernández-Cuenca F; Fernández-Domínguez...

Simultaneous and divergent evolution of resistance to cephalosporin/β-lactamase inhibitor combinations and imipenem/relebactam following ceftazidime/avibactam treatment of MDR Pseudomonas aeruginosa infections.

Alonso-García I; Vázquez-Ucha JC; Lasarte-Monterrubio C; González-Mayo E; Lada-Salvador P; Vela-Fernández R; Aja-Macaya P; Guijarro-Sánchez...

Significant increase of CTX-M-15-ST131 and emergence of CTX-M-27-ST131 Escherichia coli high-risk clones causing healthcare-associated bacteraemia of urinary origin in Spain (ITUBRAS-2 project).

Becerra-Aparicio F; Gómez-Zorrilla S; Hernández-García M; Gijón D; Siverio A; Berbel D; Sánchez-Carrillo C; Cercenado...

Recommendations of the Spanish Antibiogram Committee (COESANT) for in vitro susceptibility testing of antimicrobial agents by disk diffusion.

Rivera A; Viñado B; Benito N; Docobo-Pérez F; Fernández-Cuenca F; Fernández-Domínguez J; Guinea J; López-Navas...

Rapid Phenotypic Convergence towards Collateral Sensitivity in Clinical Isolates of Pseudomonas aeruginosa Presenting Different Genomic Backgrounds.

Hernando-Amado S; López-Causapé C; Laborda P; Sanz-García F; Oliver A; Martínez JL Abstract: Collateral sensitivity...

Pseudomonas aeruginosa antibiotic susceptibility profiles, genomic epidemiology and resistance mechanisms: a nation-wide five-year time lapse analysis.

Sastre-Femenia MÀ; Fernández-Muñoz A; Gomis-Font MA; Taltavull B; López-Causapé C; Arca-Suárez J; Martínez-Martínez L; Cantón...

Pseudomonas aeruginosa and the Complement System: A Review of the Evasion Strategies.

González-Alsina A; Mateu-Borrás M; Doménech-Sánchez A; Albertí S Abstract: The increasing emergence of multidrug resistant...

Procalcitonin and C-reactive protein to rule out early bacterial coinfection in COVID-19 critically ill patients.

Galli F; Bindo F; Motos A; Fernández-Barat L; Barbeta E; Gabarrús A; Ceccato A; Bermejo-Martin...

Phenotypic and Genotypic Antimicrobial Susceptibility Testing of Chlamydia trachomatis Isolates from Patients with Persistent or Clinical Treatment Failure in Spain.

Villa L; Boga JA; Otero L; Vazquez F; Milagro A; Salmerón P; Vall-Mayans M; Maciá...

Penicillin-Binding Protein Occupancy Dataset for 18 β-Lactams and 4 β-Lactamase Inhibitors in Neisseria gonorrhoeae

Silvia López-Argüello 1, Maria Montaner 1, Amanda Mármol-Salvador 1, Ana Velázquez-Escudero 2, 3, Fernando Docobo-Pérez...

Penicillin-Binding Protein Occupancy Dataset for 18 β-Lactams and 4 β-Lactamase Inhibitors in Neisseria gonorrhoeae

López-Argüello Silvia; Montaner Maria; Mármol-Salvador Amanda; Velázquez-Escudero Ana; Docobo-Pérez Fernando; Oliver Antonio; Moya Bartolome Abstract:...

Penicillin-Binding Protein 5/6 Acting as a Decoy Target in Pseudomonas aeruginosa Identified by Whole-Cell Receptor Binding and Quantitative Systems Pharmacology.

López-Argüello S; Montaner M; Sayed AR; Oliver A; Bulitta JB; Moya B Abstract: The β-lactam...

PBP Target Profiling by β-Lactam and β-Lactamase Inhibitors in Intact Pseudomonas aeruginosa: Effects of the Intrinsic and Acquired Resistance Determinants on the Periplasmic Drug Availability.

Montaner M; Lopez-Argüello S; Oliver A; Moya B Abstract: The lack of effective treatment options...

Outcomes of octogenarians and nonagenarians with Pseudomonas aeruginosa bacteremia: a multicenter retrospective study.

Atamna A; Margalit I; Ayada G; Babich T; Naucler P; Valik JK; Giske CG; Benito...

Mutation Analysis in Regulator DNA-Binding Regions for Antimicrobial Efflux Pumps in 17,000 Pseudomonas aeruginosa Genomes.

Pérez-Vázquez M; López-Causapé C; Corral-Lugo A; McConnell MJ; Oteo-Iglesias J; Oliver A; Martín-Galiano AJ Abstract:...

Molecular characterization of a suspected IMP-type carbapenemase-producing Pseudomonas aeruginosa outbreak reveals two simultaneous outbreaks in a tertiary-care hospital.

Gual-de-Torrella A; López-Causape C; Alejo-Cancho I; Rojo-Molinero E; Sanchez-García G; Cortés-Lara S; Rodríguez Moral MB;...

Mixed strain pathogen populations accelerate the evolution of antibiotic resistance in patients.

Diaz Caballero J; Wheatley RM; Kapel N; López-Causapé C; Van der Schalk T; Quinn A;...

Mechanisms of antibiotic resistance in Pseudomonas aeruginosa biofilms.

Fernández-Billón M; Llambías-Cabot AE; Jordana-Lluch E; Oliver A; Macià MD Abstract: Pseudomonas aeruginosa is a...

La nueva generación de vacunas de ARN mensajero (ARNm) frente a la gripe

Reina Jordi Abstract: Enfermedades Infecciosas y Microbiología Clínica: 2023 doi: 10.1016/j.eimc.2021.07.009 https://doi.org/doi: 10.1016/j.eimc.2021.07.009...

Key Factors Associated With Pulmonary Sequelae in the Follow-Up of Critically Ill COVID-19 Patients.

González J; de Batlle J; Benítez ID; Torres G; Santisteve S; Targa ADS; Gort-Paniello C;...

In vitro evolution of cefepime/zidebactam (WCK 5222) resistance in Pseudomonas aeruginosa: dynamics, mechanisms, fitness trade-off and impact on in vivo efficacy

Isabel Barceló 1, Gabriel Cabot 1, Snehal Palwe 2, Prashant Joshi 2, Swapna Takalkar 2...

In vitro dynamics and mechanisms of cefiderocol resistance development in wild-type, mutator and XDR Pseudomonas aeruginosa.

Gomis-Font MA; Sastre-Femenia MÀ; Taltavull B; Cabot G; Oliver A Abstract: To analyse the dynamics...

Impact of adherence to individual quality-of-care indicators on the prognosis of bloodstream infection due to Staphylococcus aureus: a prospective observational multicentre cohort.

Escrihuela-Vidal F; Kaasch AJ; Von Cube M; Rieg S; Kern WV; Seifert H; Song KH;...

Hyperinflammatory Immune Response in COVID-19: Host Genetic Factors in Pyrin Inflammasome and Immunity to Virus in a Spanish Population from Majorca Island.

Martínez-Pomar N; Cunill V; Segura-Guerrero M; Pol-Pol E; Escobar Oblitas D; Pons J; Ayestarán I;...

Genetic Characterization of Non-Lymphogranuloma venereum Chlamydia trachomatis Indicates Distinct Infection Transmission Networks in Spain.

Piñeiro L; Villa L; Salmerón P; Maciá MD; Otero L; Vall-Mayans M; Milagro A; Bernal...

Fever and migratory nodules in the lung.

Alonso Carballo A; Belzunce Capó JF; Iglesias Escobar C; García Gasalla M Abstract: Enfermedades infecciosas...

Executive summary of the consensus document of the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC) on the diagnosis and antimicrobial treatment of infections due to carbapenem-resistant Gram-negative bacteria.

Pintado V; Ruiz-Garbajosa P; Aguilera-Alonso D; Baquero-Artigao F; Bou G; Cantón R; Grau S; Gutiérrez-Gutiérrez...

Executive summary of the consensus document of the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC) on the diagnosis and antimicrobial treatment of infections due to carbapenem-resistant Gram-negative bacteria.

Pintado V; Ruiz-Garbajosa P; Aguilera-Alonso D; Baquero-Artigao F; Bou G; Cantón R; Grau S; Gutiérrez-Gutiérrez...

Environmental surveillance of Pseudomonas aeruginosa in recreational waters in tourist facilities of the Balearic Islands, Spain (2016-2019).

Doménech-Sánchez A; Laso E; Albertí S Abstract: Pseudomonas aeruginosa is a major opportunistic human pathogen...

Enhancing SARS-CoV-2 Surveillance through Regular Genomic Sequencing in Spain: The RELECOV Network.

Vázquez-Morón S; Iglesias-Caballero M; Lepe JA; Garcia F; Melón S; Marimon JM; García de Viedma...

Endocarditis caused by Neisseria bacilliformis: a case report and review of literature.

Gavalda M; Vilchez H; Martin ML; Ruiz E; Ribas MA; Riera M Abstract: A 58-years-old...

Elevated complement C3 and increased CD8 and type 1 helper lymphocyte T populations in patients with post-COVID-19 condition.

Garcia-Gasalla M; Berman-Riu M; Rodriguez A; Iglesias A; Fraile-Ribot PA; Toledo-Pons N; Pol-Pol E; Ferré-Beltrán...

Effectiveness of fosfomycin trometamol as oral step-down therapy for bacteraemic urinary tract infections due to MDR Escherichia coli: a post hoc analysis of the FOREST randomized trial.

Sojo-Dorado J; López-Hernández I; Hernández-Torres A; Retamar-Gentil P; Merino de Lucas E; Escolà-Vergé L; Bereciartua...

Effective inhibition of PBPs by cefepime and zidebactam in the presence of VIM-1 drives potent bactericidal activity against MBL-expressing Pseudomonas aeruginosa

Bartolome Moya 1, Sachin Bhagwat 2, Gabriel Cabot 1, German Bou 3, Mahesh Patel 2...

Diagnostic accuracy of Panbio™ rapid antigen test for SARS-CoV-2 in paediatric population.

Gallardo-Alfaro L; Lorente-Montalvo P; Cañellas M; Carandell E; Oliver A; Rojo E; Riera B; Llobera...

Detection of co-infection by Herpes simplex virus type 1 and type 2 in female genital ulcers

Reina Jordi; Iglesias Carla Abstract: Revista Española de Quimioterapia: 2023 doi:10.37201/req/041.2023 https://doi.org/doi:10.37201/req/041.2023...

CRISPR-Cas13a-Based Assay for Accurate Detection of OXA-48 and GES Carbapenemases.

Ortiz-Cartagena C; Pablo-Marcos D; Fernández-García L; Blasco L; Pacios O; Bleriot I; Siller M; López...

Comparative Analysis of Peptidoglycans From Pseudomonas aeruginosa Isolates Recovered From Chronic and Acute Infections

Gabriel Torrens 1, María Escobar-Salom 1, Elisabet Pol-Pol 1, Cristina Camps-Munar 1, Gabriel Cabot 1...

Comparative analysis of in vitro dynamics and mechanisms of ceftolozane/tazobactam and imipenem/relebactam resistance development in Pseudomonas aeruginosa XDR high-risk clones

María A Gomis-Font 1, 2, Gabriel Cabot 1, 2, Silvia López-Argüello 1, Laura Zamorano 1...

Ceftolozane/tazobactam plus tobramycin against free-floating and biofilm bacteria of hypermutable Pseudomonas aeruginosa epidemic strains: Resistance mechanisms and synergistic activity.

Agyeman AA; López-Causapé C; Rogers KE; Lucas DD; Cortés-Lara S; Gomis-Font MA; Fraile-Ribot P; Figuerola...

Ceftolozane-Tazobactam against Pseudomonas aeruginosa Cystic Fibrosis Clinical Isolates in the Hollow-Fiber Infection Model: Challenges Imposed by Hypermutability and Heteroresistance.

Tait JR; Harper M; Cortés-Lara S; Rogers KE; López-Causapé C; Smallman TR; Lang Y; Lee...

Cefiderocol resistance genomics in sequential chronic Pseudomonas aeruginosa isolates from cystic fibrosis patients.

López-Causapé C; Maruri-Aransolo A; Gomis-Font MA; Penev I; Castillo MG; Mulet X; de Dios Caballero...

Biochemical Insights into Imipenem Collateral Susceptibility Driven by ampC Mutations Conferring Ceftolozane/Tazobactam Resistance in Pseudomonas aeruginosa.

Cabot G; Kim K; Mark BL; Oliver A; Khajehpour M Abstract: Several Pseudomonas aeruginosa AmpC...

Bacterial virulence regulation through soluble peptidoglycan fragments sensing and response: knowledge gaps and therapeutic potential.

Escobar-Salom M; Barceló IM; Jordana-Lluch E; Torrens G; Oliver A; Juan C Abstract: Given the...

Are GES carbapenemases underdiagnosed? An allelic discrimination assay for their accurate detection and differentiation

Pablo-Marcos D.; Siller M.; Agüero J.; Álvarez-Justel A.; García-Fernández S.; de la Fuente S. Velasco;...

Antimicrobial stewardship in hospitals: Expert recommendation guidance document for activities in specific populations, syndromes and other aspects (PROA-2) from SEIMC, SEFH, SEMPSPGS, SEMICYUC and SEIP.

Cercenado E; Rodríguez-Baño J; Alfonso JL; Calbo E; Escosa L; Fernández-Polo A; García-Rodríguez J; Garnacho...

An increase in erythromycin resistance in methicillin-susceptible Staphylococcus aureus from blood correlates with the use of macrolide/lincosamide/streptogramin antibiotics. EARS-Net Spain (2004-2020).

El Mammery A; Ramírez de Arellano E; Cañada-García JE; Cercenado E; Villar-Gómara L; Casquero-García V;...

Activity of Imipenem-Relebactam against a Large Collection of Pseudomonas aeruginosa Clinical Isolates and Isogenic β-Lactam-Resistant Mutants

Pablo A Fraile-Ribot 1, Laura Zamorano 1, Rocío Orellana 1, Ester Del Barrio-Tofiño 1, Irina...

A paper biosensor for overcoming matrix effects interfering with the detection of sputum pyocyanin with competitive immunoassays.

Adrover-Jaume C; Clemente A; Rodríguez-Urretavizcaya B; Vilaplana L; Marco MP; Rojo-Molinero E; Oliver A; de...

A Genomic Snapshot of the SARS-CoV-2 Pandemic in the Balearic Islands

Carla López-Causapé 1, 2, Pablo A Fraile-Ribot 1, 2, Santiago Jiménez-Serrano 1 , Gabriel Cabot...

[EDP-938, a new antiviral with inhibitory activity against the nucleoprotein of the respiratory syncytial virus].

Reina J; Iglesias C Abstract: The absence of an effective vaccine against respiratory syncytial virus...

[Alternative viral diagnosis in suspected monkeypox].

Reina J; González de Herrero E Abstract: Revista espanola de quimioterapia : publicacion oficial de...

2022

[Changes in the incidence and clinical manifestations of paediatric respiratory infections of viral aetiology during the SARS-CoV-2 pandemic].

Díaz Pérez D; Reina J; Arcay RM; Osona B Abstract: Enfermedades infecciosas y microbiologia clinica:...

[Nirmatrelvir plus ritonavir (Paxlovid) a potent SARS-CoV-2 3CLpro protease inhibitor combination].

Reina J; Iglesias C Abstract: All coronavirus, including SARS-CoV-2, encode two proteases needed for the...

[Possible effect of the “original antigenic sin” in vaccination against new variants of SARS-CoV-2].

Reina J Abstract: Revista clinica espanola: 2022 doi: 10.1016/j.rce.2021.05.003 https://pubmed.ncbi.nlm.nih.gov/34108737...

[The Victoria and Yamagata Lineages of Influenza B Viruses, unknown and undervalued].

Reina J Abstract: The influenza virus B belongs to the family Orthomyxoviriridae and to the...

Activity of cefiderocol, imipenem/relebactam, cefepime/taniborbactam and cefepime/zidebactam against ceftolozane/tazobactam- and ceftazidime/avibactam-resistant Pseudomonas aeruginosa.

Lasarte-Monterrubio C; Fraile-Ribot PA; Vázquez-Ucha JC; Cabot G; Guijarro-Sánchez P; Alonso-García I; Rumbo-Feal S; Galán-Sánchez...

Acute retinal necrosis caused by herpes simplex type 2.

Reina J; Costa C; Fernández-Billón M Abstract: Medicina clinica: 2022 doi: 10.1016/j.medcli.2022.06.004 https://pubmed.ncbi.nlm.nih.gov/36088127...

ATP Bioluminescence Assay To Evaluate Antibiotic Combinations against Extensively Drug-Resistant (XDR) Pseudomonas aeruginosa.

Puig-Collderram B; Domene-Ochoa S; Salvà-Comas M; Montero MM; Duran X; González JR; Grau S; Oliver...

CARB-ES-19 Multicenter Study of Carbapenemase-Producing Klebsiella pneumoniae and Escherichia coli From All Spanish Provinces Reveals Interregional Spread of High-Risk Clones Such as ST307/OXA-48 and ST512/KPC-3.

Cañada-García JE; Moure Z; Sola-Campoy PJ; Delgado-Valverde M; Cano ME; Gijón D; González M; Gracia-Ahufinger...

Carbapenem Combinations for Infections Caused by Carbapenemase-Producing Pseudomonas aeruginosa: Experimental In Vitro and In Vivo Analysis

Herrera-Espejo Soraya; Del Barrio-Tofiño Ester; Cebrero-Cangueiro Tania; López-Causapé Carla; Álvarez-Marín Rocío; Cisneros José Miguel; Pachón...

Cardiac Arrest Following Unsuspected Self-Poisoning With Doxylamine

Gomila Isabel; Socias Antonia; Socias Lorenzo; Gutierrez Leticia; Ripoll Tomas; Alarcón Francisco Javier; García Ana...

Changes in the incidence and clinical manifestations of paediatric respiratory infections of viral aetiology during the SARS-CoV-2 pandemic.

Díaz Pérez D; Reina J; Arcay RM; Osona B Abstract: Enfermedades infecciosas y microbiologia clinica...

Comparative analysis of in vitro dynamics and mechanisms of ceftolozane/tazobactam and imipenem/relebactam resistance development in Pseudomonas aeruginosa XDR high-risk clones.

Gomis-Font MA; Cabot G; López-Argüello S; Zamorano L; Juan C; Moyá B; Oliver A Abstract:...

Comparison of Ceftolozane/Tazobactam Infusion Regimens in a Hollow-Fiber Infection Model against Extensively Drug-Resistant Pseudomonas aeruginosa Isolates.

Montero MM; Domene-Ochoa S; López-Causapé C; López-Montesinos I; Luque S; Sorlí L; Campillo N; Padilla...

Current Positioning against Severe Infections Due to Klebsiella pneumoniae in Hospitalized Adults.

Vidal-Cortés P; Martin-Loeches I; Rodríguez A; Bou G; Cantón R; Diaz E; De la Fuente...

Dissolvable Polymer Valves for Sweat Chrono-Sampling in Wearable Paper-Based Analytical Devices.

Vaquer A; Barón E; de la Rica R Abstract: Paper sensors with colorimetric signal transduction...

Duration of Treatment for Pseudomonas aeruginosa Bacteremia: a Retrospective Study.

Babich T; Naucler P; Valik JK; Giske CG; Benito N; Cardona R; Rivera A; Pulcini...

Effects of Inhaled Corticosteroids on the Innate Immunological Response to Pseudomonas aeruginosa Infection in Patients with COPD.

Cerón-Pisa N; Shafiek H; Martín-Medina A; Verdú J; Jordana-Lluch E; Escobar-Salom M; Barceló IM; López-Causapé...

Fluconazole-resistant Candida parapsilosis clonally related genotypes: first report proving the presence of endemic isolates harbouring the Y132F ERG11 gene substitution in Spain.

Alcoceba E; Gómez A; Lara-Esbrí P; Oliver A; Beltrán AF; Ayestarán I; Muñoz P; Escribano...

Fluidoterapia en la sepsis y el shock séptico

Sa Marcio Borges; Salaverría Iñigo; Cabas Antonio Couto Abstract: Medicina Intensiva: 2022 doi: 10.1016/j.medin.2022.03.012 https://doi.org/doi:...

Gut to lung translocation and antibiotic mediated selection shape the dynamics of Pseudomonas aeruginosa in an ICU patient

Wheatley Rachel M.; Caballero Julio Diaz; van der Schalk Thomas E.; De Winter Fien H...

Hemithioindigo-Based Visible Light-Activated Molecular Machines Kill Bacteria by Oxidative Damage.

Santos AL; van Venrooy A; Reed AK; Wyderka AM; García-López V; Alemany LB; Oliver A;...

Imipenem-Relebactam Susceptibility in Enterobacterales Isolates Recovered from ICU Patients from Spain and Portugal (SUPERIOR and STEP Studies).

Hernández-García M; García-Castillo M; Bou G; Cercenado E; Delgado-Valverde M; Oliver A; Pitart C; Rodríguez-Lozano...

Impact of Aspergillus spp. isolation in the first 24 hours of admission in critically ill patients with severe influenza virus pneumonia.

Claverias L; Daniel X; Martín-Loeches I; Vidal-Cortez P; Gómez-Bertomeu F; Trefler S; Zaragoza R; Borges-Sa...

Impact of Peptidoglycan Recycling Blockade and Expression of Horizontally Acquired β-Lactamases on Pseudomonas aeruginosa Virulence.

Barceló IM; Torrens G; Escobar-Salom M; Jordana-Lluch E; Capó-Bauzá MM; Ramón-Pallín C; García-Cuaresma D; Fraile-Ribot...

Improved cytometric analysis of untouched lung leukocytes by enzymatic liquefaction of sputum samples.

Santopolo G; Clemente A; Rojo-Molinero E; Fernández S; Álvarez MC; Oliver A; de la Rica...

Improving the Quantification of Colorimetric Signals in Paper-Based Immunosensors with an Open-Source Reader

Russell Steven M.; Alba-Patiño Alejandra; Vaquer Andreu; Clemente Antonio; de la Rica Roberto Abstract: Measuring...

In vitro activity of imipenem/relebactam against Pseudomonas aeruginosa isolates recovered from ICU patients in Spain and Portugal (SUPERIOR and STEP studies).

Hernández-García M; García-Castillo M; Melo-Cristino J; Pinto MF; Gonçalves E; Alves V; Vieira AR; Ramalheira...

In vivo translational assessment of the GES genotype on the killing profile of ceftazidime, ceftazidime/avibactam and meropenem against Pseudomonas aeruginosa.

Gill CM; Oliver A; Fraile-Ribot PA; Nicolau DP Abstract: To evaluate the in vivo killing...

Increased mRNA Levels of ADAM17, IFITM3, and IFNE in Peripheral Blood Cells Are Present in Patients with Obesity and May Predict Severe COVID-19 Evolution.

Pomar CA; Bonet ML; Ferre-Beltrán A; Fraile-Ribot PA; García-Gasalla M; Riera M; Picó C; Palou...

Light-activated molecular machines are fast-acting broad-spectrum antibacterials that target the membrane.

Santos AL; Liu D; Reed AK; Wyderka AM; van Venrooy A; Li JT; Li VD;...

Low Ciprofloxacin Concentrations Select Multidrug-Resistant Mutants Overproducing Efflux Pumps in Clinical Isolates of Pseudomonas aeruginosa.

Sanz-García F; Hernando-Amado S; López-Causapé C; Oliver A; Martínez JL Abstract: Low antibiotic concentrations present...

Mammals’ humoral immune proteins and peptides targeting the bacterial envelope: from natural protection to therapeutic applications against multidrug-resistant Gram-negatives.

Escobar-Salom M; Torrens G; Jordana-Lluch E; Oliver A; Juan C Abstract: Mammalian innate immunity employs...

Micro- and nanosensors for detecting blood pathogens and biomarkers at different points of sepsis care.

Alba-Patiño A; Vaquer A; Barón E; Russell SM; Borges M; de la Rica R Abstract:...

Plasma-induced nanoparticle aggregation for stratifying COVID-19 patients according to disease severity.

Santopolo G; Clemente A; González-Freire M; Russell SM; Vaquer A; Barón E; Aranda M; Socias...

Polymer Components for Paper‐Based Analytical Devices

González del Campo Maríadel Mar; Vaquer Andreu; de la Rica Roberto Abstract: AbstractIn recent years...

Possible effect of the “original antigenic sin” in vaccination against new variants of SARS-CoV-2.

Reina J Abstract: Revista clinica espanola: 2022 doi: 10.1016/j.rceng.2021.05.005 https://pubmed.ncbi.nlm.nih.gov/34563486...

Possible effect of the “original antigenic sin” in vaccination against new variants of SARS-CoV-2

Reina J. Abstract: Revista Clínica Española (English Edition): 2022 doi:10.1016/j.rceng.2021.05.005 https://doi.org/doi:10.1016/j.rceng.2021.05.005...

Prevalence of the fimbrial operon mrkABCD, mrkA expression, biofilm formation and effect of biocides on biofilm formation in carbapenemase-producing Klebsiella pneumoniae isolates belonging or not belonging to high-risk clones.

Gual-de-Torrella A; Delgado-Valverde M; Pérez-Palacios P; Oteo-Iglesias J; Rojo-Molinero E; Macià MD; Oliver A; Pascual...

Rapid Identification and Classification of Pathogens That Produce Carbapenemases and Cephalosporinases with a Colorimetric Paper-Based Multisensor.

Santopolo G; Clemente A; Rojo-Molinero E; Oliver A; Noé C; de la Rica R Abstract:...

Recommendations for the management of critically ill patients with COVID-19 in Intensive Care Units.

Vidal-Cortés P; Díaz Santos E; Aguilar Alonso E; Amezaga Menéndez R; Ballesteros MÁ; Bodí MA;...

Reinforcement of the Standard Therapy with Two Infusions of Convalescent Plasma for Patients with COVID-19: A Randomized Clinical Trial.

Bargay-Lleonart J; Sarubbo F; Arrizabalaga M; Guerra JM; Borràs J; El Haji K; Flexas M;...

Role of Enzymatic Activity in the Biological Cost Associated with the Production of AmpC β-Lactamases in Pseudomonas aeruginosa.

Barceló IM; Jordana-Lluch E; Escobar-Salom M; Torrens G; Fraile-Ribot PA; Cabot G; Mulet X; Zamorano...

Safety, efficacy, and pharmacokinetics of gremubamab (MEDI3902), an anti-Pseudomonas aeruginosa bispecific human monoclonal antibody, in P. aeruginosa-colonised, mechanically ventilated intensive care unit patients: a randomised controlled trial.

Chastre J; François B; Bourgeois M; Komnos A; Ferrer R; Rahav G; De Schryver N;...

Selection of AmpC β-Lactamase Variants and Metallo-β-Lactamases Leading to Ceftolozane/Tazobactam and Ceftazidime/Avibactam Resistance during Treatment of MDR/XDR Pseudomonas aeruginosa Infections

Ruedas-López Alba; Alonso-García Isaac; Lasarte-Monterrubio Cristina; Guijarro-Sánchez Paula; Gato Eva; Vázquez-Ucha Juan Carlos; Vallejo Juan...

Simulated Intravenous versus Inhaled Tobramycin with or without Intravenous Ceftazidime Evaluated against Hypermutable Pseudomonas aeruginosa via a Dynamic Biofilm Model and Mechanism-Based Modeling.

Bilal H; Tait JR; Lang Y; Zhou J; Bergen PJ; Peleg AY; Bulitta JB; Oliver...

Spread of SARS-CoV-2 in hospital areas.

Grimalt JO; Vílchez H; Fraile-Ribot PA; Marco E; Campins A; Orfila J; van Drooge BL;...

Staphylococcus aureus surface protein G (sasG) allelic variants: correlation between biofilm formation and their prevalence in methicillin-resistant S. aureus (MRSA) clones.

Carrera-Salinas A; González-Díaz A; Vázquez-Sánchez DA; Camoez M; Niubó J; Càmara J; Ardanuy C; Martí...

Suboptimal Concentrations of Ceftazidime/Avibactam (CAZ-AVI) May Select for CAZ-AVI Resistance in Extensively Drug-Resistant Pseudomonas aeruginosa: In Vivo and In Vitro Evidence

Lopez-Montesinos Inmaculada; Montero María Milagro; Domene-Ochoa Sandra; López-Causapé Carla; Echeverria Daniel; Sorlí Luisa; Campillo Nuria;...

Susceptibility profiles and resistance genomics of Pseudomonas aeruginosa isolates from European ICUs participating in the ASPIRE-ICU trial.

Torrens G; van der Schalk TE; Cortes-Lara S; Timbermont L; Del Barrio-Tofiño E; Xavier BB;...

2021

[Impact of hygienic and social distancing measures against SARS-CoV-2 on respiratory infections caused by other viruses].

Reina J; Arcay RM; Busquets M; Machado H Abstract: To control the pandemic caused by...

[Impact of spike genetic variants in vaccines against SARS-CoV-2].

Reina J; Fraile-Ribot P Abstract: Vacunas: 2021 doi: 10.1016/j.vacun.2021.04.001 https://pubmed.ncbi.nlm.nih.gov/33867900...

[Plitidepsin, an inhibitor of the cell elongation factor eEF1a, and molnupiravir an analogue of the ribonucleoside cytidine, two new chemical compounds with intense activity against SARS-CoV-2].

Reina J Abstract: The knowledge of the replicative cycle of SARS-CoV-2 and its interactions with...

[Use of dried blood from the heel (Guthrie card) in the diagnosis of congenital enterovirus infection].

Reina J; Dueñas J; Fraile P Abstract: Anales de pediatria: 2021 doi: 10.1016/j.anpedi.2019.12.002 https://pubmed.ncbi.nlm.nih.gov/31917177...

In Vivo Evolution of GES β-Lactamases Driven by Ceftazidime/Avibactam Treatment of Pseudomonas aeruginosa Infections

Fraile-Ribot Pablo A.; Fernández Javier; Gomis-Font María A.; Forcelledo Lorena; Mulet Xavier; López-Causapé Carla; Oliver...

6-Halopyridylmethylidene Penicillin-Based Sulfones Efficiently Inactivate the Natural Resistance of Pseudomonas aeruginosa to β-Lactam Antibiotics.

Vázquez-Ucha JC; Rodríguez D; Lasarte-Monterrubio C; Lence E; Arca-Suarez J; Maneiro M; Gato E; Perez...

A Genomic Snapshot of the SARS-CoV-2 Pandemic in the Balearic Islands.

López-Causapé C; Fraile-Ribot PA; Jiménez-Serrano S; Cabot G; Del Barrio-Tofiño E; Prado MC; Linares JM;...

A Large Multicenter Prospective Study of Community-Onset Healthcare Associated Bacteremic Urinary Tract Infections in the Era of Multidrug Resistance: Even Worse than Hospital Acquired Infections?

Gómez-Zorrilla S; Becerra-Aparicio F; López Montesinos I; Ruiz de Gopegui E; Grau I; Pintado V;...

Activity of imipenem/relebactam against a Spanish nationwide collection of carbapenemase-producing Enterobacterales.

Vázquez-Ucha JC; Seoane-Estévez A; Rodiño-Janeiro BK; González-Bardanca M; Conde-Pérez K; Martínez-Guitián M; Alvarez-Fraga L; Arca-Suárez...

Combination versus monotherapy as definitive treatment for Pseudomonas aeruginosa bacteraemia: a multicentre retrospective observational cohort study.

Babich T; Naucler P; Valik JK; Giske CG; Benito N; Cardona R; Rivera A; Pulcini...

Correction to: The evolution of the ventilatory ratio is a prognostic factor in mechanically ventilated COVID-19 ARDS patients.

Torres A; Motos A; Riera J; Fernández-Barat L; Ceccato A; Pérez-Arnal R; García-Gasulla D; Peñuelas...

Detection of respiratory viruses in patients with suspected SARS-CoV-2 infection.

Reina J; Suarez L; Lara P Abstract: Enfermedades infecciosas y microbiologia clinica (English ed.): 2021...

Distinct epidemiology and resistance mechanisms affecting ceftolozane/tazobactam in Pseudomonas aeruginosa isolates recovered from ICU patients in Spain and Portugal depicted by WGS.

Hernández-García M; García-Castillo M; García-Fernández S; Melo-Cristino J; Pinto MF; Gonçalves E; Alves V; Vieira...

Emergence of Resistance to Novel Cephalosporin-β-Lactamase Inhibitor Combinations through the Modification of the Pseudomonas aeruginosa MexCD-OprJ Efflux Pump.

Gomis-Font MA; Pitart C; Del Barrio-Tofiño E; Zboromyrska Y; Cortes-Lara S; Mulet X; Marco F;...

Evaluation of Rapid Polymyxin Pseudomonas test in clinical Pseudomonas aeruginosa isolates with various degrees of multidrug resistance.

Sánchez-López J; Cortés-Cuevas JL; Díez-Aguilar M; López-Causapé C; Cantón R; Morosini MI Abstract: Pseudomonas aeruginosa...

Evolution, Clinical and Microbiological Characteristics of Invasive Pneumococcal Disease since the Introduction of the Pneumococcal Conjugate Vaccine 13-Valent in Adults over 18 Years Old.

Buades J; Losada I; González-Moreno J; Peñaranda M; Vilaplana L; Roda N; Rey A; Rodriguez...

Immunodetection of Lung IgG and IgM Antibodies against SARS-CoV-2 via Enzymatic Liquefaction of Respiratory Samples from COVID-19 Patients.

Clemente A; Alba-Patiño A; Santopolo G; Rojo-Molinero E; Oliver A; Borges M; Aranda M; Del...

Impact of ceftolozane/tazobactam concentrations in continuous infusion against extensively drug-resistant Pseudomonas aeruginosa isolates in a hollow-fiber infection model.

Montero MM; Domene-Ochoa S; López-Causapé C; Luque S; Sorlí L; Campillo N; Padilla E; Prim...

In vitro evolution of cefepime/zidebactam (WCK 5222) resistance in Pseudomonas aeruginosa: dynamics, mechanisms, fitness trade-off and impact on in vivo efficacy.

Barceló I; Cabot G; Palwe S; Joshi P; Takalkar S; Periasamy H; Cortés-Lara S; Zamorano...

Influenza vaccination in the time of SARS-CoV-2.

Reina J Abstract: Medicina clinica (English ed.): 2021 doi: 10.1016/j.medcle.2020.10.003 https://pubmed.ncbi.nlm.nih.gov/33521306...

Inhaled corticosteroid dose is associated with Pseudomonas aeruginosa infection in severe COPD.

Shafiek H; Verdú J; Iglesias A; Ramon-Clar L; Toledo-Pons N; Lopez-Causape C; Juan C; Fraile-Ribot...

Metagenomics Analysis Reveals an Extraordinary Inner Bacterial Diversity in Anisakids (Nematoda: Anisakidae) L3 Larvae

Arcos Susana C.; Lira Felipe; Robertson Lee; González María Rosa; Carballeda-Sangiao Noelia; Sánchez-Alonso Isabel; Zamorano...

Mobile origami immunosensors for the rapid detection of urinary tract infections.

Adrover-Jaume C; Rojo-Molinero E; Clemente A; Russell SM; Arranz J; Oliver A; de la Rica...

Molecular Analysis of the Contribution of Alkaline Protease A and Elastase B to the Virulence of Pseudomonas aeruginosa Bloodstream Infections.

Mateu-Borrás M; Zamorano L; González-Alsina A; Sánchez-Diener I; Doménech-Sánchez A; Oliver A; Albertí S Abstract:...

Molecular Basis of AmpC β-Lactamase Induction by Avibactam in Pseudomonas aeruginosa: PBP Occupancy, Live Cell Binding Dynamics and Impact on Resistant Clinical Isolates Harboring PDC-X Variants.

López-Argüello S; Montaner M; Oliver A; Moya B Abstract: Avibactam belongs to the new class...

Molecular mechanisms driving the in vivo development of OXA-10-mediated resistance to ceftolozane/tazobactam and ceftazidime/avibactam during treatment of XDR Pseudomonas aeruginosa infections.

Arca-Suárez J; Lasarte-Monterrubio C; Rodiño-Janeiro BK; Cabot G; Vázquez-Ucha JC; Rodríguez-Iglesias M; Galán-Sánchez F; Beceiro...

Multicenter Performance Evaluation of MALDI-TOF MS for Rapid Detection of Carbapenemase Activity in Enterobacterales: The Future of Networking Data Analysis With Online Software.

Gato E; Anantharajah A; Arroyo MJ; Artacho MJ; Caballero JD; Candela A; Chudějová K; Constanso...

Neisseria gonorrhoeae antimicrobial resistance in Spain: a prospective multicentre study.

Salmerón P; Viñado B; Arando M; Alcoceba E; Romero B; Menéndez B; Bernal S; Idigoras...

Norovirus outbreak causing gastroenteritis in a hotel in Menorca, Spain.

Doménech-Sánchez A; Laso E; Genestar E; Berrocal CI Abstract: To establish the agent responsible for...

Panbio™ rapid antigen test for SARS-CoV-2 has acceptable accuracy in symptomatic patients in primary health care.

Bulilete O; Lorente P; Leiva A; Carandell E; Oliver A; Rojo E; Pericas P; Llobera...

Pharmacodynamics of ceftazidime plus tobramycin combination dosage regimens against hypermutable Pseudomonas aeruginosa isolates at simulated epithelial lining fluid concentrations in a dynamic in vitro infection model.

Tait JR; Bilal H; Kim TH; Oh A; Peleg AY; Boyce JD; Oliver A; Bergen...

Poor agreement between clinical screening and universal pre-procedure SARS-CoV-2 PCR testing prior to endoscopy.

Khorrami Minaei S; Garrido Durán C; García Hernández M; García Amengual I; Mena Ribas A...

Predicting Pseudomonas aeruginosa susceptibility phenotypes from whole genome sequence resistome analysis

Cortes-Lara Sara; Barrio-Tofiño Ester del; López-Causapé Carla; Oliver Antonio; Martínez-Martínez Luis; Bou Germán; Zamorano Laura;...

Predictive Immunological, Virological, and Routine Laboratory Markers for Critical COVID-19 on Admission.

García-Gasalla M; Ferrer JM; Fraile-Ribot PA; Ferre-Beltrán A; Rodríguez A; Martínez-Pomar N; Ramon-Clar L; Iglesias...

Procedimientos en Microbiología Clínica (número 71, 2.a edición 2021)

Abstract: Enfermedades Infecciosas y Microbiología Clínica: 2021 doi: 10.1016/j.eimc.2021.05.005 https://doi.org/doi: 10.1016/j.eimc.2021.05.005...

Pseudomonas aeruginosa Susceptibility in Spain: Antimicrobial Activity and Resistance Suppression Evaluation by PK/PD Analysis.

Valero A; Rodríguez-Gascón A; Isla A; Barrasa H; Del Barrio-Tofiño E; Oliver A; Canut A;...

Pseudomonas aeruginosa: a clinical and genomics update.

Pelegrin AC; Palmieri M; Mirande C; Oliver A; Moons P; Goossens H; van Belkum A...

Rapid evolution and host immunity drive the rise and fall of carbapenem resistance during an acute Pseudomonas aeruginosa infection.

Wheatley R; Diaz Caballero J; Kapel N; de Winter FHR; Jangir P; Quinn A; Del...

Recommendations for antibiotic selection for severe nosocomial infections.

Mensa J; Barberán J; Ferrer R; Borges M; Rascado P; Maseda E; Oliver A; Marco...

Spread of a SARS-CoV-2 variant through Europe in the summer of 2020.

Hodcroft EB; Zuber M; Nadeau S; Vaughan TG; Crawford KHD; Althaus CL; Reichmuth ML; Bowen...

Surveillance for Enteroviruses Associated with Hand, Foot, and Mouth Disease, and Other Mucocutaneous Symptoms in Spain, 2006-2020.

Martínez-López N; Muñoz-Almagro C; Launes C; Navascués A; Imaz-Pérez M; Reina J; Romero MP; Calvo...

The first wave of the COVID-19 epidemic in Spain was associated with early introductions and fast spread of a dominating genetic variant.

López MG; Chiner-Oms Á; García de Viedma D; Ruiz-Rodriguez P; Bracho MA; Cancino-Muñoz I; D'Auria...

Time-Kill Evaluation of Antibiotic Combinations Containing Ceftazidime-Avibactam against Extensively Drug-Resistant Pseudomonas aeruginosa and Their Potential Role against Ceftazidime-Avibactam-Resistant Isolates.

Montero MM; Domene Ochoa S; López-Causapé C; Luque S; Sorlí L; Campillo N; López Montesinos...

Validation of MALDI-TOF for the early detection of the ST175 high-risk clone of Pseudomonas aeruginosa in clinical isolates belonging to a Spanish nationwide multicenter study

Mulet Xavier; Fernández-Esgueva Marta; Norte Cristina; Zamorano Laura; del Barrio-Tofiño Ester; Oliver Antonio Abstract: Enfermedades...

Whole-genome sequence-guided PCR for the rapid identification of the Pseudomonas aeruginosa ST175 high-risk clone directly from clinical samples.